Hi & Welcome.
It can cause a life threatening reaction, hence should't be taken together.
Concerta (
Methylphenidate) may increase the blood levels and side effects of antidepressant medication Prozac (Fluoxetine) including a rare but serious condition called the
serotonin syndrome which is characterized by confusion, hallucination, seizures, extremely high BP,
increased heart rate, fever,
excessive sweating, shivering,
blurred vision, severe muscle stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
In severe cases it may result in coma and death.
Contact your treatomg doctor if you experience increased side effects or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
Hope this answers your query.
Take care.
A feedback is appreciated.