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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could You Tell Me How Binders Or Fillers Interrupt The Way A Drug Performs ?

Hello doctor, could you tell me how binders or fillers might interrupt the way a drug performs, is there a situation where someone s digestive tract doesn t properly break down a particular drug due to the binder or filler thus making the item ineffective? Thank you.
Fri, 9 Dec 2016
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General Surgeon 's  Response
Hi.
Thanks for your query.
Noted the question regarding how binders or fillers might interupt the the that can interfere with absorption, breakdown or so making the drug ineffective.
This is a very typical question. The possible answers are:
Ideally the binders and fillers are the ones that are most suitable for human intestinal tract for the medicines to break properly, work properly, release properly and so on.
Only rarely the problem of inability to breakdown and such things may come up, many a times the intestinal environment, bacterial actions, chemical composition, enzyme actions and so on can cause the disruption in the pathways and hence can cause the problem.
Occasionally the binders and fillers itself can cause reactions and hence the problem.
I hope this answers your query.
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Could You Tell Me How Binders Or Fillers Interrupt The Way A Drug Performs ?

Hi. Thanks for your query. Noted the question regarding how binders or fillers might interupt the the that can interfere with absorption, breakdown or so making the drug ineffective. This is a very typical question. The possible answers are: Ideally the binders and fillers are the ones that are most suitable for human intestinal tract for the medicines to break properly, work properly, release properly and so on. Only rarely the problem of inability to breakdown and such things may come up, many a times the intestinal environment, bacterial actions, chemical composition, enzyme actions and so on can cause the disruption in the pathways and hence can cause the problem. Occasionally the binders and fillers itself can cause reactions and hence the problem. I hope this answers your query.