Could an overdose on Topamax have the same signs and symptoms as a Norco overdose? Last night my wife started back on her Topamax after a two week headache. She was so drowsy and turned blue, we has an ocymeter her O2 was 68 and her pulse was 130ish. I took her BP and it was about 210/130. I'd swear she took Norco or diluadid, but she insists I'm wrong, little professional help, please.