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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Switching To Atorvastatin From Creator Result In Increased Memory Problems?

My husband switched from creator to atforvastatin in Dec. 5 weeks later he had an episode of transient global amnesia. He continued to have memory problems and in May he stopped taking atforvastatin. In June he had another episode of trans. Global amnesia. He had a ct scan and a mri both normal. The doctor put him back on a statin drug this time pravastin he was on it for a couple of days and after seeing a neurologist he decided to stop taking it. Then he had another episode of trans global amnesia last week. We are hoping that this is still an effect of the statin drugs still in his system. Our family Dr. And neurologist don t have any answers.
Tue, 27 Jan 2015
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Neurologist,  's  Response
I read your question and I understand your concern.

I must say however that I wouldn't see the switch from rosuvastatin (crestor) to atorvastatin as the cause. They have similar mechanism of action and side effects, actually atorvastatin may be the most used and well known statin worldwide.
I understand that the lack of explanation must be confusing to you. There is still not a clearly explained mechanism or cause for transient global amnesia, several theories like migraine variant, seizure, transient ischemic attack. None of those would have any relation to statins though, if anything statins should have a beneficial effect in case transient ischemia is the cause.

I hope things work out for the best.
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Can Switching To Atorvastatin From Creator Result In Increased Memory Problems?

I read your question and I understand your concern. I must say however that I wouldn t see the switch from rosuvastatin (crestor) to atorvastatin as the cause. They have similar mechanism of action and side effects, actually atorvastatin may be the most used and well known statin worldwide. I understand that the lack of explanation must be confusing to you. There is still not a clearly explained mechanism or cause for transient global amnesia, several theories like migraine variant, seizure, transient ischemic attack. None of those would have any relation to statins though, if anything statins should have a beneficial effect in case transient ischemia is the cause. I hope things work out for the best.