My wife is suffering from High Blood Pressure. She is 71 years old and currently taking Lisinopril 40mg, Metoprolol 50 mg, and clonidine 0.1 mg (3 times daily). The Lisinopril and Metoprolol do not seem to be effective, therefore she has to take the Clonodine 3 times a day to keep the blood pressure at or below 140/90. With just Lisinopril and Metoprolol her blood pressure can get up to 170/100. Clonidine is effective but The problem with Clonidine is that it makes here very sleepy, tired and very constipated. What BP medication/dosage would you recommend she try other than clonidine.