HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Hi, I Had A Potential Exposure To Hiv ( Unprotected

default
Posted on Thu, 11 Jun 2020
Question: hi,
i had a potential exposure to hiv ( unprotected sex with a sex worker )
at 20 day hiv duo test negetive
at 65th day hiv rna pcr test <20copies per ml(log value 1.3 )
at 75th day hive 4th gen atigen /antibody test negetive
do i need to take a test again to confirm
doctor
Answered by Dr. Sankaranantham Murugan (4 hours later)
Brief Answer:
You are almost free from HIV infection.

Detailed Answer:
Hi,
Welcome to 'Ask A Doctor' service.
Thanks for posting your query.

Two types of HIV Tests are available broadly.
1. Antibody detecting tests -They will become reactive after the window period -That is, the body will take some time to produce antibodies against any diseases. The window period for HIV infection is around 4-8 weeks.

2. Antigen detecting test - will detect the infection as early as within a week after the exposure in the presence of an infection and considered more conclusive 3-4 weeks after the exposure.
In your case, I will not give much importance to the DUO test done on the 20th day after the exposure.

HIV RNA PCR 65th day is very much reliable. But you had tested for a quantitative test (useful in assessing the prognosis, rather than diagnosis). DNA PCR and RNA qualitative PCR are more valuable for diagnosis. Anyhow the result came as < 20 copies is very much favorable that you are very much unlikely to have HIV 1 infection.

The HIV 4th generation test done on the 75th day after the exposure is very much confirmatory and conclusive. They are reliable up to 99% as it ruled out both HIV 1 and 2 infection.

One more test (Rapid or 4th generation test) 12 weeks after the exposure will be recommended to have a 100% conclusive result (especially for HIV 2 infection, as HIV 1 is already ruled out) which is a very rare possibility.

Dr S.Murugan


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
default
Follow up: Dr. Sankaranantham Murugan (7 hours later)
thanks doctor ,
great relief
the tests were done for both Hiv 1 & 2
but the rna pcr resulted "target not detected" for hiv 2
but fir hiv 1 a log value 1.3 is the result and in report interpreted as " hiv rna detected but under the range od assay"
this makes me anxious and worried .. i have attached the rna pcr results
doctor
Answered by Dr. Sankaranantham Murugan (7 hours later)
Brief Answer:
Your 4th generation HIV Combo test is highly reliable.

Detailed Answer:
Hi,
Welcome back.
Not to worry.
HIV RNA PCR quantitative results will be expressed like this only even in the absence of infection.
Because of that only, I told this test has not much value for diagnosis. It is a test to assess the prognosis of the disease. But your 4th generation HIV Combo test is highly reliable and conclusive. The nonreactive test after 10 weeks almost ruled out both HIV 1&2.
Dr S Murugan
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Sankaranantham Murugan (20 minutes later)
soo no more test required?
default
Follow up: Dr. Sankaranantham Murugan (1 minute later)
ill attach 4th gen combo test done by elisa method and reslut wag available within one hour
doctor
Answered by Dr. Sankaranantham Murugan (48 minutes later)
Brief Answer:
The report after 12 weeks ensures 100% conclusive

Detailed Answer:
Hi,
Welcome back.
I am not able to see your test report.
I will be more happy if you have one more test after 12 weeks after the exposure.
Dr S Murugan
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Sankaranantham Murugan (5 hours later)
the reports have been attached
doctor
Answered by Dr. Sankaranantham Murugan (2 hours later)
Brief Answer:
Reports can not be verified.

Detailed Answer:
Hi,
Welcome back.
I went through the reports. I am not able to see the name and date in any of the reports (The doctor before giving opinion he has to verify the same as per our guidelines). With this I should not extend any opinion on these.
Anyhow I will say these words.
It seems that you had seen HIV 2 RT PCR also and it came as Target not detected... but without any date.
Once again resend with dates if you want more from me.
Dr S.Murugan
Note: Get personalized answers to your HIV related queries You can choose to talk face to face with your doctor. Book a Video Call now.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Hi, I Had A Potential Exposure To Hiv ( Unprotected

Brief Answer: You are almost free from HIV infection. Detailed Answer: Hi, Welcome to 'Ask A Doctor' service. Thanks for posting your query. Two types of HIV Tests are available broadly. 1. Antibody detecting tests -They will become reactive after the window period -That is, the body will take some time to produce antibodies against any diseases. The window period for HIV infection is around 4-8 weeks. 2. Antigen detecting test - will detect the infection as early as within a week after the exposure in the presence of an infection and considered more conclusive 3-4 weeks after the exposure. In your case, I will not give much importance to the DUO test done on the 20th day after the exposure. HIV RNA PCR 65th day is very much reliable. But you had tested for a quantitative test (useful in assessing the prognosis, rather than diagnosis). DNA PCR and RNA qualitative PCR are more valuable for diagnosis. Anyhow the result came as < 20 copies is very much favorable that you are very much unlikely to have HIV 1 infection. The HIV 4th generation test done on the 75th day after the exposure is very much confirmatory and conclusive. They are reliable up to 99% as it ruled out both HIV 1 and 2 infection. One more test (Rapid or 4th generation test) 12 weeks after the exposure will be recommended to have a 100% conclusive result (especially for HIV 2 infection, as HIV 1 is already ruled out) which is a very rare possibility. Dr S.Murugan