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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will you have itching with Keflex and Amoxicillin?

Answered by
Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 15822 Questions

Posted on Thu, 7 Jun 2018 in Medicines and Side Effects
Question: Hi, At one point I'd had an itching hive kind of reaction to Reflex. Since then when needed Ive taken Z-pacs, but wonder if Amoxicillin is also an option with that history.

Thats Keflex and autocorrect keeps changing that..
Thank you
Answered by Dr. Michelle Gibson James 54 minutes later
Brief Answer:
slight small risk of reaction

Detailed Answer:
Hi, thanks for using healthcare magic

Keflex is in the family of meds/antibiotics called cephalosporin. It is one of the first generation of cephalosporins to be developed.

There is some cross reactivity or sensitivity with amoxicillin. This means that some persons that are allergic to cephalosporin , may also be allergic to amoxicillin and vice versa.
This risk is about 1 % or occurs in 1 out of 100 persons with this allergy.

This means that there is a very slight change of allergic reaction

I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

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