Question: Hello. My name is XXXXXXX About 2 years ago, during a routine doctor visit, labs showed my hemoglobin and platelets to be low (hbg around 10.5 and plt around 120). About 6 months later, my hemoglobin dropped to around 8.6 and platelets dropped to aound 80 and have stayed there for the last 15 months. I have had a bone marrow biopsy which showed a few abnormalities but low blasts. Later it was discovered that my spleen was enlarged to 20 cm with a lesion/mass of I think 9 cm. A PET scan showed hotspots in the spleen and a few lymph nodes in the neck (suv for spleen around 2.6, suv for lymph nodes around 4). Lymph nodes were removed and results showed benign and consistant with being reactive. I have been tested for rheumatoid and other auto immune disorders and all are negative. My doctor now is recommending removal of the spleen. My question is whether this is a good option or are there medicinal therapies that could be tried.

Hello, thanks for your reply. Some follow-up. My Liver enzymes are normal, BUN and SCr are normal. My LDH is norml and has always been. Haptoglobin is normal while reticulocytes are high (3.31). IgA, IgG and IgM are normal.
Hep B and Hep C antibody are non reactive. ANA and RA qualitative are negative.
Thanks