Question: I and a 64 year old female with a history of recent polymorphic Vtach without syncope. An ICD was implanted in March 2015 for prevention. My Cardiac XXXXXXX was negative for any Cardiac Disease. Apparently my EKG is classic for Brugada syndrome but my EPS for diagnosis was negative.
Although I have had a history of PVC's, Atrial Tachycardia, and uni focal V-tach at times in the past, since I have had the ICD, the PVC's have increased tremendously and are very frequent...Bigeminy/Trigeminy. I have been on Toprol (alone) (25mg bid) , then Sotalol, 80mg bid) and now Mexiletine (150mg tid) and Toprol (12.5mg/day) with no improvement. The frequency of the PVC's are erratic, sometimes make me lightheaded, and slight weakness in my upper legs. I am so frustrated. It is difficult to plan events because I don't know how I will feel. I am afraid to take Amiodarone due to the numerous serious potential side effects. I do not drink any alcohol or any coffee. Prior to this, I ran 3 miles 3-4 times/week. My pacemaker is set at 75/min to hopefully prevent V-tach but my normal pulse runs between 64-68. Any ideas is appreciated.

Update: Medication is Mexiletine 150mg tid plus Topral 12.5mg/day