Does Crushing A Pill And Using It, Cause Reduced Medicinal Effects On Consumption?
Question: my husband is 89 and the skin on his front part pf his leg sluffing off and leaving a large rectangular area (3x6 inches) THAT IS constantly oozing fluid his trouser legs are always wet. Doc proscribed furosemide. hr wont takr it what if I mash it up and put in his foo? Thanks, worried wife.
Brief Answer:
Bioavailability of the drug reduces.
Detailed Answer:
Hello Ma'am,
I can certainly understand your concern.I have worked through your attached query in detail.
Bioavailability,(fraction of drug available for systemic absorption)often decreases when a pill is crushed and mixed with food .
But if he is really adamant in taking the pill, you have no option Left.
Hope I have answered your query.
Let me know if I can assist you further.
Regards,
Dr. Suresh Heijebu,
General & Family Physician.
Bioavailability of the drug reduces.
Detailed Answer:
Hello Ma'am,
I can certainly understand your concern.I have worked through your attached query in detail.
Bioavailability,(fraction of drug available for systemic absorption)often decreases when a pill is crushed and mixed with food .
But if he is really adamant in taking the pill, you have no option Left.
Hope I have answered your query.
Let me know if I can assist you further.
Regards,
Dr. Suresh Heijebu,
General & Family Physician.
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation
Above answer was peer-reviewed by :
Dr. Yogesh D