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Could You Review The T1-MPRAGE Images (I Will Attach) Acquired

Posted on Mon, 2 Dec 2019

Question: Could you review the T1-MPRAGE images (I will attach) acquired at 3T MRI (Siemens Prisma)? The CSF seemed to be covering an area that is a bit larger than usual. Thanks.

Answered by Dr. Vivek Chail (6 hours later)

Brief Answer:
Your observation is correct

Detailed Answer:
Hi,
Thanks for writing in to us.

There is generalised prominent cortical sulci and CSF spaces in the attached images from the link given. I agree to you r observation and the fluid area is more in the bilateral frontal parietal convexity.

In many people this finding is not significant.

However it is important to know the reason for the scan and the clinical symptoms in detail.

Regards,

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Vivek Chail (4 hours later)

Thank you very much Dr. Chail.

This was a scan that was acquired during a research study. So, this is an incidental finding.

That being said, I was wondering if there are any diseases (like Alzheimer's, Parkinson's, epilepsy, hydrocephalus, etc.) where this composition is commonly observed. Furthermore, does it signal something like brain shrinkage, memory loss and so on?

Many thanks.

Answered by Dr. Vivek Chail (14 hours later)

Brief Answer:
Findings are more likely part of normal

Detailed Answer:
Hi,
Thanks for writing back.

The changes are more likely to be a part of the normal spectrum if there are no neurological signs.

There is no hydrocephalus, the left lateral ventricle is mildly prominent and likely physiological.

Epilepsy is a big spectrum of disorders involving seizures and needs detailed examination should there be seizures.

Alzheimers and Parkinsons are less likely to be visualised at 34 years age and the imaging findings take years to appear.

Regards,

Above answer was peer-reviewed by : Dr. Nagamani Ng