Question: I am 45 yrs old and have been having bizarre symptoms for the past 5 months. It started out with sudden onset of eye pain (like someone was tugging at my eye from behind). That progressed to severe daily headaches like a vice around my head and temples and very sinus pressure feeling. I went to ENT and he gave me decongestants and nothing really worked. This lasted on and off for a few months, tapering off to just a vague pressure feeling. Then in the past month or so after a bad virus and late nights at work, I started to get an "adrenaline" feeling in my chest when I was trying to fall asleep. Eventually it progressed from my chest to my head, and then I developed severe insomnia from it. On nights I was able to sleep, I would wake up feeling like I was fainting. (Ive always had some sleep paralysis, type issues, but this felt different -truly like passing out). Then I developed a very alarming and persistent occipital headache. Like a clenching or cramping feeling. It started to come on with waves of head pressure rushes and extreme ear pain. I was hospitalized and had several brain MRI and MRAs all negative. FUll body CT scan showed some calcified mediastinal lymph nodes. Pheochromocytoma negative. Ultimately, doctors said migraines. Then after I was released from the hospital, I started getting waves of dizziness (and one of true vertigo) with arrhythmia, accelerating heatbeat for about 20 seconds and a heavy angina pain and then it would go away and return 20 to 30 minutes later (this happened all night and was very scary). (I had a mitral valve repair 5 yrs ago so I am familiar with palpitations - this was not regular palps). A subsequent holter monitor was negative though. My dr. put me on Klonopin but on some nights I still have extreme insomnia where I am unable to sleep at all because the minute I lay down, I get the head rushes and ear and head pressure, or when I start drifting off I get the back of the head headache. I also have been living with 4 weeks of neck pain. I wouldnt really call it pain so much as a burning sensation when you press on my trapezius and neck does feel a little pulled. Even when you push on my occipital bones they hurt. ANd my gums ache and have ear pressure and aches and eye pain too. My eye dr said he thought he saw some optic nerve blurred margin but the MRI was okay though). My neuro is at a loss and feels maybe its some form of sleep apnea or anxiety precipitated by the virus and adrenaline rushes. We are going to do an EEG and lumbar puncture in the next two weeks. I have posted this to a few other specialists but I have a special reason for asking to an oncologist. About 15 yrs ago I had very weird host of symptoms (eventually chalked up possibly to some bizarre immune reaction to doxycline). Anyway as part of that workout they did a bone marrow biopsy. It came back negative however chromosome genetic testing of the marrow showed a deletion of 46xxdel(4)(q21q35) which "indicated a lymphoproliferative disorder, myeloma or lymphoma." However, no one could find any evidence of cancer in me and could not really say what to make of it. Is it possible that I have been living with some type of cancerous disease for 15 years and not know it? I have no weight loss, or fatigue, blood counts are all good and can workout without pain. I am concerned that the neck and headaches are some metastatic condition to the brain or spine such as lepotimengeal carcinoma even though in the year I have had a CT scan of chest and abdomen (not enhanced), an upper GI endoscopy, abdominal ultrasound, pelvic ultrasound, 3 enhanced brain MRIs, a neck xray and a head and neck MRA - most of it in the last 5 months. I know this sounds completely insane, but it is very troubling to me to have these symptoms and no explanation, so now I am becoming irrational and worrying that I have had cancer all these years and it never showed up. Thanks for you patience, I know you are dealing with very sick patients and I don't want to waste your time, just need some reassurance as some of the other doctors in the other specialties have provided. My dr. suggested that since it may be anxiety based to go to a PT and he felt my neck and occipitals an said I was all knotted up. Just wondering if it would indicate any primary cancer somewhere in me. Thanks.