Can methylprednisolone cause a problems while taking Warfarin Sodium. I
Risk of increased bleeding
Hello and welcome to Ask a Doctor service.
I have reviewed your query and here is my advice.
Methylprednisone can increase the bleeding tendencies when taken for prolonged periods. The metabolism of warfarin can be decreased when combined with methylprednisone. Therefore INR should be monitored regularly when taking methylprednisone and warfarin together. If needed, dose of warfarin or methylprednisone is to be decreased. You can discuss with your treating doctor about it and get the doses changed.
Hope this helps. Let me know if I can assist you further.