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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can methylprednisolone cause a problems while taking Warfarin Sodium. I

Answered by
Dr. Vaishalee Punj

General & Family Physician

Practicing since :2003

Answered : 2144 Questions

Posted on Thu, 24 Jan 2019 in Internal Doctor Category
Question: Can methylprednisolone cause a problems while taking Warfarin Sodium. I went to doctor upon waking and not being able to hear..Not even my own voice. He gave me methylprednisolone... I am taking Warfarin.Will these 2 drugs have bad interactions? OR OTHER SUGGESTIONS?
Answered by Dr. Vaishalee Punj 1 hour later
Brief Answer:
Risk of increased bleeding

Detailed Answer:
Hello and welcome to Ask a Doctor service.

I have reviewed your query and here is my advice.

Methylprednisone can increase the bleeding tendencies when taken for prolonged periods. The metabolism of warfarin can be decreased when combined with methylprednisone. Therefore INR should be monitored regularly when taking methylprednisone and warfarin together. If needed, dose of warfarin or methylprednisone is to be decreased. You can discuss with your treating doctor about it and get the doses changed.

Hope this helps. Let me know if I can assist you further.
Dr Vaishalee
Above answer was peer-reviewed by : Dr. Vaishalee Punj

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