Can chemotherapy cause inflammation under the biopsy scar tissue?
I meant to say that his Pet Scan was clear in November.
No chance of recurrence
After hearing the history I think as the pet scan was clear in November there is no chance of recurrence after such a long time.
The raised nodule in the biopsy area is a keloid tissue which is a benign condition and there is no chance of malignancy returning.
Chemotherapy has caused this raised nodule formation as it had killed all the cancer cells which have to lead to the formation of this nodule and it consists mostly of dead cells.
If it is bothering then it can be surgically removed by excision by a general surgeon
Hope I have answered your query. Let me know if I can assist you further.
Punch biopsy suggested
I have gone through your picture.
As your husband has a history of melanoma and is undergoing chemotherapy for lung cancer and now has tenderness in the area where the biopsy was taken so many years ago.
And you can visually see inflammation of tissue underneath the skin adjacent to the scar but there is no discolouration on the epidermis and can palpate a 2-inch circular growth that is immovable and his PET scan in November is normal but still.
I would advise him to undergo a punch biopsy to rule out recurrence on the scar
In a punch biopsy, a tool is used which looks like a tiny round cookie cutter to remove a deeper sample of skin.
The punch biopsy tool on the skin is rotated until it cuts through all the layers of the skin.
The sample is removed and studied by pathologists to rule out any recurrence.
The edges of the biopsy site are often stitched together.
You can consult a general surgeon for punch biopsy
Melanoma can recur after 10 years in more than 6 Percent of patients.
Hope I have answered your query.
Dr Monish De, Oncologist