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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Augmentin cause elevated liver enzymes and subsequent liver damage?

Answered by
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Dr. Suresh Heijebu

General & Family Physician

Practicing since :2010

Answered : 3536 Questions

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Posted on Thu, 12 Jul 2018 in Digestion and Bowels
Question: I was on a course of Augmentin for a sinus infection. Caused elevated liver enzymes. these are my numbers the day after quitting Augmentin. Quit the drug 2 days ago, these are my labs from yesterday.,
ALT 459, AST 205, Total Bili 3.3, Direct Bili 2.0, ALk phos157. No jaundice, urine a little dark. Stool alittle light one time. No itching, swelling or abd pain. Low grade fever and body aches gone now. I suffer from health anxiety , and am looking for a little reassurance as I go down this path. I tend to go to the dark side " cybercondria". I am a nurse. Am I headed for liver failure? In your opinion, prognosis and length of time for liver to return to normal. Would milk thistle help or am I just adding more drugs for the liver to process. As you can tell, I am very anxious about this and am searching for some positives. As of course I read into the worse case scenerios in pubmed studies etc.. Thank you in advance, I will wait for your reply and then NO MORE RESEARCH ! XXXXXXX
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Answered by Dr. Suresh Heijebu 14 hours later
Brief Answer:
Ultrasound abdomen scan is mandatory

Detailed Answer:
Hello Madam
I can certainly understand your concern

I have worked through your query in detail

These parameters certainly reflect a significant damage of liver. But the possibility of liver failure is unlikely.

Also Augmentin induced liver damage seems to be unlikely.

It's very important to evaluate your lab parameters though ultrasound abdomen at the earliest.

Further management if any is largely based on test results.

Avoid fried and fatty food stuff. Milk thistle helps.

Review with reports to determine further course of action.

Post your further queries if any

Thank you



Above answer was peer-reviewed by : Dr. Nagamani Ng
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