My wife is 24 week pregnant . during last week ultrasound Dr told us there is single echogenic foci in the left ventrical of baby s heart . As per her it is a marker of Trisomy 21. however the definative test to ascertain is amniocentesis . we are worried after this as amnio carries risk of miscarriage at 1:200. we want to know how much serious is this finding are we are worrying too much ? does risk of having down sydrome baby is increased for my wife and if by how much. my wife haven t undergone tripple screen test. does Down syndrome is heridetry as wife parents are perfectly normal.