Intrauterine insemination success rates vary considerably and depend on: age of the woman,type of ovarian stimulation used (if any),duration of infertility ,cause of infertility,number and quality of motile sperm. Intrauterine insemination has very little chance of working in women over 40 years old. IUI has also been shown to have a reduced success rate in younger women with a significantly elevated day 3 FSH level, or other indications of significantly reduced ovarian reserve. With significant male factor issues, IVF with ICSI is indicated and has high success rates for women under age 40. The risk for complications with intrauterine insemination is very low. The woman could develop an infection in the uterus and tubes from bacterial contamination that originated either in the semen sample, or through a contamination of the sterile catheter in the vagina or cervical area during the procedure. Careful cleaning of the cervix and cautious technique make this a rarity.