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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Taking Benadryl Help Cure Reaction Caused Due To IV Cleocin?

If a paitent experiences an allergic reaction to IV Cleo and is treated with benadryl and Tylenol and the IV site cannot be changed; how long should further antibiotic treatment be held (given that the antibiotic is DCd and replaced with another)? Should we wait for the half-life of benadryl to pass so as to not cover symptoms of a second allergy (the patient was unaware of the original allergy). Are there any published resources regarding this?
Fri, 7 Aug 2015
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General & Family Physician,  's  Response
Hello
Thank You for contacting HCM.

Whenever there is allergic reaction to drug then immediate treatment includes i/v steroid & antihistamine dose. Reaction usually gets limited within few hours. After 4-6 hrs antibiotic can be given BUT same antibiotic group is avoided. Patients are in that case given alternative(second class) antibiotic for treatment. I would suggest to wait for at least 6 hrs and then start further medication.

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Wishing you good health.
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Will Taking Benadryl Help Cure Reaction Caused Due To IV Cleocin?

Hello Thank You for contacting HCM. Whenever there is allergic reaction to drug then immediate treatment includes i/v steroid & antihistamine dose. Reaction usually gets limited within few hours. After 4-6 hrs antibiotic can be given BUT same antibiotic group is avoided. Patients are in that case given alternative(second class) antibiotic for treatment. I would suggest to wait for at least 6 hrs and then start further medication. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. Wishing you good health.