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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Wife Is Pregnant. Wife Is B Negative, And I Am B Positive. Tested For ICT Positive. Now Titres Increased. Problem?

hi, my wife is in the 6th month of pregnancy. she is B negative and i am B positive. she was testted for ICT positive but in low titres of 1:8 till completion of fifth month. but today titres has increased from 1:8 to 1:128. what complications are possible? is it necessary that complications will occur. should she continue with her pregnancy? pl suggest
Wed, 22 May 2013
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OBGYN,  's  Response
Hello,
Any rise of the titres above 1 in 16 indicates that there is more of antibody formation and given the raised levels in your wife, the levels are critical. The course of the pregnancy may be decided by doing a spectrophotometric analysis of the amniotic fluid and based on the results, it may be decided whether to continue with the pregnancy or to terminate it. Anti-D is not going to help at this stage. Please consult an experienced high risk practitioner and receive further management. Hope your query is answered. Good luck.
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Wife Is Pregnant. Wife Is B Negative, And I Am B Positive. Tested For ICT Positive. Now Titres Increased. Problem?

Hello, Any rise of the titres above 1 in 16 indicates that there is more of antibody formation and given the raised levels in your wife, the levels are critical. The course of the pregnancy may be decided by doing a spectrophotometric analysis of the amniotic fluid and based on the results, it may be decided whether to continue with the pregnancy or to terminate it. Anti-D is not going to help at this stage. Please consult an experienced high risk practitioner and receive further management. Hope your query is answered. Good luck.