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What to do in case of severe tonic seizure ?

My son, who is 33 years old, has been suffering from intermittent epileptic seizures (TONIC) with certain psychotic problems like low self-confidence, poor concentration and dis-interest in work , non-socialization, rare but sudden bursts of anger etc. From September, 1998 to July, 2011, he had in all 43 irregular seizures. He has been on different medicines for cure since 1998 itself as per different neurologists advice in the order given- DILANTIN-100+100mg/day ( 1 seizure in 1 year intake during 1998-99); TEGRETOL-100+100mg / d ( 2 in 4 months - 1999); ZEPTOL- 200+200 mg / d (30 in 2 yrs -1999-2001); EPILAX CHRONO 700+700 mg / d ( 3 in 4 yrs- 2002-2006); DEPAKOTE -500+500mg / d (NIL in 8 months-2007); TORVATE -500+500 mg/d +T.EPTOIN-100mg/d (7 in 4 yrs-2008-11). 20% of the seizures were due to non-intake of medicine for a day or two and rest may be due to non-suitability or inadequate dosage of medicines taken. presently he is on EPILAX CHRONO -500+500 mg / d +RISDONE-1 mg/d+NEXITO-5 mg/d from July, 2011. Today, ie on 16-4-2012 he is on severe tonic seizure twice at 1.30 AM and 5.30AM. Advice sought to do what immediately.
Asked On : Thu, 19 Apr 2012
Answers:  1 Views:  150
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Neurologist 's  Response

Thanks for using

From the details provided it looks to me like he is suffering from pseudo-medically refractory epilepsy along with psychosis and depression. I call it pseudo because of the inadequate dose and poor compliance with the medications. Other causes for recurrent seizures are sleep deprivation and wrong selection of medications for the type of epilepsy.

I recommend you to see a Epileptologist for classification of epilepsy and then to choose right medicine for the type of epilepsy. Inspite of this he remains refractory with good drug compliance he needs Video-EEG for surgical evaluation.


Dr Shiva Kumar R
Consultant Neurologist & Epileptologist
Answered: Fri, 20 Apr 2012
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