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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Precautions Should Be Taken For Thalassemia During Pregnancy?

My wife is thalesemia minor and her blood groupd is B Rh Negative. She is into her 7th month of pregnancy and her Haemoglobin level is 9.6. What kind of specific precautions we need to take. Also is there a need to arrange for blood during her delivery. I am not thalesemia carrier and my blood group is B Rh Positive.                                                                  
Fri, 4 Mar 2016
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OBGYN,  's  Response
Hi there,
Welcome to HCM,

A hemoglobin of 9.6 is on the lower side though its what's expected in a thalessemia minor patient.

Yes its better that she delivers in a well equipped hospital which has adequate B negative blood which is cross matched to her kept ready for her if required.

The negative blood group also is slightly more difficult to arrange and should be kept in mind .

Since you are yourself not a thalessemia carrier it implies that the baby will not be affected by thalessemia.

Your wife will need to do her anti-D titres at 28 weeks and if negative she should take inj. Rhogam 1500 IU at 28 weeks and again after delivery of baby if baby blood group is Rh positive she should repeat the inj. Rhogam within 72 hours of birth.

This is to prevent her from being sensitized to the Rh positive red cells and can prevent complications in future babies.

Hope this helps.
Regards.
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What Precautions Should Be Taken For Thalassemia During Pregnancy?

Hi there, Welcome to HCM, A hemoglobin of 9.6 is on the lower side though its what s expected in a thalessemia minor patient. Yes its better that she delivers in a well equipped hospital which has adequate B negative blood which is cross matched to her kept ready for her if required. The negative blood group also is slightly more difficult to arrange and should be kept in mind . Since you are yourself not a thalessemia carrier it implies that the baby will not be affected by thalessemia. Your wife will need to do her anti-D titres at 28 weeks and if negative she should take inj. Rhogam 1500 IU at 28 weeks and again after delivery of baby if baby blood group is Rh positive she should repeat the inj. Rhogam within 72 hours of birth. This is to prevent her from being sensitized to the Rh positive red cells and can prevent complications in future babies. Hope this helps. Regards.