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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The MRI Scan Show?

Hi: Had an MRI of brain because of some hearing loss. Part of the report stated, There are scattered nonspecific foci of high signal abnormality in the periventricular white matter as seen the FLAIR images, likely reflecting areas of gliosis, demyelination and /or chronic ischemic changes . I am 59 years old, female, whose dad had MS for over 50 years. No intracranial pathology or abnormal enhancement noted. Could you tell me what this means?
Mon, 1 Sep 2014
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Radiologist,  's  Response
Hello
Thanks for writing to HCM

Abnormal periventricular signal in the form of hyperintense FLAIR sequences may be related to ischemic changes resulting from involvement of small blood vessels,demyelination,gliosis etc.
Ischemic changes resulting from blood vessels changes in diseases like hypertension,diabetes mellitus,dyslipidemia.
So,you need monitoring of conditions that leads to ischemic changes like hypertension,altered lipid profile,diabetes mellitus so that further progression of disease can be halted.
You need investigations like routine hemogram,RBS,LFT,RFT,Lipid profile,ultrasound of abdomen.
Proper treatment depend upon findings.

You also need follow up scan,it is necessary for ruling out demyelinating diseases. Demyelinating disease like MS are associated with many neurological findings,it should be clinically correlated.

Hope i have answered your query.
Take Care
Dr.Indu Bhushan
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What Does The MRI Scan Show?

Hello Thanks for writing to HCM Abnormal periventricular signal in the form of hyperintense FLAIR sequences may be related to ischemic changes resulting from involvement of small blood vessels,demyelination,gliosis etc. Ischemic changes resulting from blood vessels changes in diseases like hypertension,diabetes mellitus,dyslipidemia. So,you need monitoring of conditions that leads to ischemic changes like hypertension,altered lipid profile,diabetes mellitus so that further progression of disease can be halted. You need investigations like routine hemogram,RBS,LFT,RFT,Lipid profile,ultrasound of abdomen. Proper treatment depend upon findings. You also need follow up scan,it is necessary for ruling out demyelinating diseases. Demyelinating disease like MS are associated with many neurological findings,it should be clinically correlated. Hope i have answered your query. Take Care Dr.Indu Bhushan