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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Cal25 Value 18 From Chemotherapy For Ovarian Cancer Indicate?

Dear sir,
I have ovarian cancer detected in july and ca125 value is 12.8 then i've completed operation in july end and after 45 days ca125 value shows 8 then i have taken a 3 chemotheraphy cycle and now my ca125 value shows 18. kindly advice above steps....
Mon, 6 Jul 2015
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Pulmonologist,  's  Response
Thanks for your question on Health Care Magic.
I can understand your concern.
CA 125 is tumour marker which indicates tumour activity.
So it is used in patients who had surgical removal or taken chemotherapy.
It is very good marker to suspect relapse or worsening of cancer. You initially had higher CA 125 levels. Than after surgery your level is decreased. This is due to decrease in tumour burden because of surgical removal.
But again value raised after chemotherapy. So this indicates, worsening of underlying malignancy.
So in my opinion, you should consult your cancer doctor and get done repeat CT scan to rule out worsening of underlying tumour.
Hope I have solved your query.
I will be happy to help you further. Wish you good health. Thanks.
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What Does Cal25 Value 18 From Chemotherapy For Ovarian Cancer Indicate?

Thanks for your question on Health Care Magic. I can understand your concern. CA 125 is tumour marker which indicates tumour activity. So it is used in patients who had surgical removal or taken chemotherapy. It is very good marker to suspect relapse or worsening of cancer. You initially had higher CA 125 levels. Than after surgery your level is decreased. This is due to decrease in tumour burden because of surgical removal. But again value raised after chemotherapy. So this indicates, worsening of underlying malignancy. So in my opinion, you should consult your cancer doctor and get done repeat CT scan to rule out worsening of underlying tumour. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.