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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Do Sperm Agglutination And Clumping Mean In The Following Sperm Analysis?

sir, tell your comments Semen Analysis Test Result Flag Unit Reference Ranqe Physical Examination Colour Grey White Liquefaction more than one hours min Up to 30 Up to 30 min Viscosity Higly viscos Volume 2.5 ml 2m1 or more pH 8.0 7.2 - 8.0 Total Sperm Count 15.5 20 million /ml or more Microscopic Examination WBC s 2 - 4 HPF RBC s 4 - 6 HPF Normal forms Motility 30 Minutes Post Ejaculation Highly progressive 8 Moderately progressive 15 Sluggish motility 45 Non motile 32 Motility lhrs. Post Ejaculation Highly progressive 5 Moderately progressive 10 Sluggish motility 40 Non motile 45 Motility 2hrs. Post Ejaculation Highly progressive 2 Moderately progressive Comments : Sprem aggulatination and clumping
Mon, 6 Jun 2016
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General & Family Physician 's  Response
Hi,

Thanks for posting in HCM.

I understand your concern.

The following conclusions can be inferred based on the semen analysis report you have enclosed.
1. Colour should be ideally whitish or slight yellow, but is grey white.
2. Liquification is delayed, as normally should happen by 30 minutes.
3. Viscosity is also more than normal as it is indicating highly viscous.
4. Volume and pH seems to be fine with 2.5 ml and 8.0.
5. Microscopy showing few WBCs and RBCs could indicate the presence of infection.
6. Sperm motility seems to be less than normal with sluggishly motile and non-motile forms being more in %.

Ideally, semen after liquification should be clear with no agglutination or clumping. Since it is seen here, the reasons could be due to the presence of sperm antibodies. Agglutinated sperm clump together in huge masses and would be unable to migrate through the cervix and uterus, leading to male infertility. The extent of this is determined by amount of agglutination and mobility % of the sperms.

Administration of antibiotics to cure infection, along with vitamin E and vitamin C supplements are known to reduce clumping.

Hope the information provided would be helpful.
All the best.
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What Do Sperm Agglutination And Clumping Mean In The Following Sperm Analysis?

Hi, Thanks for posting in HCM. I understand your concern. The following conclusions can be inferred based on the semen analysis report you have enclosed. 1. Colour should be ideally whitish or slight yellow, but is grey white. 2. Liquification is delayed, as normally should happen by 30 minutes. 3. Viscosity is also more than normal as it is indicating highly viscous. 4. Volume and pH seems to be fine with 2.5 ml and 8.0. 5. Microscopy showing few WBCs and RBCs could indicate the presence of infection. 6. Sperm motility seems to be less than normal with sluggishly motile and non-motile forms being more in %. Ideally, semen after liquification should be clear with no agglutination or clumping. Since it is seen here, the reasons could be due to the presence of sperm antibodies. Agglutinated sperm clump together in huge masses and would be unable to migrate through the cervix and uterus, leading to male infertility. The extent of this is determined by amount of agglutination and mobility % of the sperms. Administration of antibiotics to cure infection, along with vitamin E and vitamin C supplements are known to reduce clumping. Hope the information provided would be helpful. All the best.