Hello Thanks for writing to us with your health concern. There are various reasons for being unable to conceive. Firstly, it could be her age. Some women have less ovarian reserve, with age, the capacity of the ovaries to form mature eggs, declines. Also, she could be having blocked fallopian tubes. THese are the ducts that carry the sperms right to the egg leading to fertilization. There could be an issue with her husband s semen analysis. Also, ovulation could be a problem. Hormonal imbalances, genetic abnormalities, infections, - all these can lead to difficulties in conception. Please ask her to consult a fertility specialist. Take regular folic acid supplements, and maintain an ideal BMI Take care.