Hello Welcome in H.C.M. Regarding your query for swollen lymph nodes on neck of your wife after having sexual contact and oral sex with some one else. Here I would like totell you that enlarged lymph nodes on neck is indicative of some inflammatory pathology going on in oral cavity, oropharynx, nasopharynx and larynx. Since your wife had played unprotected oral sex with some one, so if his genital was having infection than that is bound to give infection to oral cavity and oropharynx. For diagnosis and treatment point of view it is very important to know about type of infection and to which antibiotic it is most sensitive. So you are advice for these basic investgations- 1- Culture and sensitivity of throat swab. 2- Gram s staining of throat swab. 3- FNAC from enlarged nevk glands. With the help of inferences of above investigation one can identify the causative infective agent and accordingly that can be manage. Regards.