My symptoms are as follows: Joint pain, primarily SI joint, low back, neck, knees, hands & wrists. Stiffness and reduced mobility in neck and waist. Stiffness worse in morning. Fatigue & difficulty sleeping 50% of time Migraine (min 1 per week) weakness in hands plantar faciitis type pain test results have all come back fine except for elevated hs-crp, slightly elevated MPV, elevated leukocytes in urinalysis, and an ill-defind gamma globulin. Pain gradually getting worse over last 18 months. No relief from rest. Pain is severe much of the time. finally found a Dr willing to listen instead of brushing me off and we are waiting on test results for HLA-B27 gene and peripheral joint xrays. Currently my lumbar and hip xrays are normal except for mild osteoarthritis in lumbar spine. I have read stories of Ankylosing spondylitis and have found many parallels to my experience. In your opinion would these symptoms/results point to a probable diagnosis of AS? Family history of lupus and various arthritis. Thank you