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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Heart Burn And Burping While On Pantoprazole?

I ve been taking a daily dose of 40 mg Pantoprazole (Protonix substitute) for acid reflux for several years. About 5 weeks ago I started having some heartburn with some burping. I went to my doctor about a week ago and he told me to either take my medication twice a day for a month or try the over-the-counter 24 hour Nexium twice a day. I took two Pantoprazole Friday through Sunday, but the heartburn seemed to be getting worse, so Monday evening I switched to taking Nexium twice a day. It has not seemed too help much. In fact I had heartburn with some burping all evening yesterday and all day today. It lets off some, but never seems to go away completely. I ve also taken Tums a couple of times today. Since I have been taking my medication twice a day I think it has gotten worse instead of improving. I am not eating or drinking any of the common trigger foods such as caffiene, sodas, chocolate,or super spicy foods. Any ideas?
Mon, 3 Oct 2016
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Gastroenterologist,  's  Response
Since you have already been on a proton pump inhibitor since long, and have now developed new symptoms of heart burn, I'm wondering if you are actually suffering from reflux disease or not.
When symptoms don't resolve despite PPIs, other causes need to be looked for, and under such circumstances, testing for esophageal pH, some blood tests, and an endoscopy might be helpful.
Alternatively, you might have developed a small intestinal bacterial overgrowth secondary to the prolonged use of PPIs, I suggest a simple course of antibiotic might help. Certainly, you should revisit your doctor.
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What Causes Heart Burn And Burping While On Pantoprazole?

Since you have already been on a proton pump inhibitor since long, and have now developed new symptoms of heart burn, I m wondering if you are actually suffering from reflux disease or not. When symptoms don t resolve despite PPIs, other causes need to be looked for, and under such circumstances, testing for esophageal pH, some blood tests, and an endoscopy might be helpful. Alternatively, you might have developed a small intestinal bacterial overgrowth secondary to the prolonged use of PPIs, I suggest a simple course of antibiotic might help. Certainly, you should revisit your doctor.