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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevation Of LFT Parameters And Total Bilirubin While Under Chemo?

sir, my patient is periampullary adenocarcinoma with locally advanced stage, given gencitabin 1000 mg and oxaplatin 100 mg 4 days back, now total bilirubin is 2.2 in comparison to 1.5 before application of chemo, alkaline phosphate comes down to 612 from 685, other LFT parameters elevated moderately, kindly comment on state of health of my patient,
Wed, 27 May 2015
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Hematologist,  's  Response
Hi, dear
I have gone through your question. I can understand your concern.
Your patients has periampullary adenocarcinoma. He is taking gemcitabin and oxaplatin. Oxaplatin can cause transient elevations of liver enzymes. You should keep close watch on liver enzymes. If level increase further then it can be due to oxaplatin toxicity and you need to stop oxaplatin.
Hope I have answered your question, if you have any doubts then contact me at bit.ly/Drsanghvihardik, I will be happy to answer you.
Thanks for using health care magic.
Wish you a very good health.
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What Causes Elevation Of LFT Parameters And Total Bilirubin While Under Chemo?

Hi, dear I have gone through your question. I can understand your concern. Your patients has periampullary adenocarcinoma. He is taking gemcitabin and oxaplatin. Oxaplatin can cause transient elevations of liver enzymes. You should keep close watch on liver enzymes. If level increase further then it can be due to oxaplatin toxicity and you need to stop oxaplatin. Hope I have answered your question, if you have any doubts then contact me at bit.ly/Drsanghvihardik, I will be happy to answer you. Thanks for using health care magic. Wish you a very good health.