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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Effects Of High Calcium In A Child?

I am writing this in hopes to find medical help for my daughter. She is 8yrs old and has had high calcium since sept of this year. Her calcium can gone as high at 15.5. My daughter has been hospitalized 3 times in the last couple of months do to this. We are from Carson City, Nv. Renown hospital was unable to find what was causing this and sent her to Sunrise childrens hospital in las vegas, nv. We have been here for a little over 2 weeks and the doctors here are unable to find a reason. her heart and kidneys have been effected. The doctors were able to get her calcium levels back to normal by using Pamidronate Disodium Aredia. its been 3 days since she was given the drug and the doctors want to send her home. I was informed by the doctors that they don t know what is causing the high calcium and they think in a few weeks to a month her calcium will go back up, as soon as the medication is out of her system. Please I need your help! My Name is Yvonne Salas My contact info. Email YYYY@YYYY
Tue, 7 Jul 2015
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Pediatrician 's  Response
Hi, I had gone through your question and understand your concerns. My opinion is that you should not worry so much about it now unless the diagnosis is confirmed. We should differentiate next statements:
- primary hyperparathyroidism(check parathormon);
- manifestation of vitamin D intoxication(check level of Vitamin D);
- Williams syndrome, tubulopathy (consult genetics);
- leukemia, lymphoma, myeloma, neuroblastoma, hepatocellular carcinoma(consult haematologist, oncologist);
- after chronic ingestion of vitamin A;
-Hypophosphatasia, a metabolic bone disease characterized by bone and teeth hypomineralization due to defective function of tissue-nonspecific alkaline phosphatase (TNSALP), is also associated with hypercalcemia.
- Familial hypocalciuric hypercalcemia - an autosomal dominant disorder
You should avoid severe hypercalcemia,it can affect the nervous system and cause weakness, hypotonia with proximal myopathy, lethargy and stupor, and rarely seizures. Hypercalcemia can also induce polyuria and dehydration, diabetes insipidus, nephrocalcinosis .
I would suggest you:
- reduced calcium diet(avoid milk products, cheese and etc.);
- continue pamidronate,it is inhibitor of bone resorption;
- consume food enriched with Potassium, because it is Calcium antagonist(apricot, raisins,banana,potato and etc.)
If you do not have any clarifications, you can close the discussion and rate the answer. Wish your daughter speedy recovery and good health!
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What Are The Effects Of High Calcium In A Child?

Hi, I had gone through your question and understand your concerns. My opinion is that you should not worry so much about it now unless the diagnosis is confirmed. We should differentiate next statements: - primary hyperparathyroidism(check parathormon); - manifestation of vitamin D intoxication(check level of Vitamin D); - Williams syndrome, tubulopathy (consult genetics); - leukemia, lymphoma, myeloma, neuroblastoma, hepatocellular carcinoma(consult haematologist, oncologist); - after chronic ingestion of vitamin A; -Hypophosphatasia, a metabolic bone disease characterized by bone and teeth hypomineralization due to defective function of tissue-nonspecific alkaline phosphatase (TNSALP), is also associated with hypercalcemia. - Familial hypocalciuric hypercalcemia - an autosomal dominant disorder You should avoid severe hypercalcemia,it can affect the nervous system and cause weakness, hypotonia with proximal myopathy, lethargy and stupor, and rarely seizures. Hypercalcemia can also induce polyuria and dehydration, diabetes insipidus, nephrocalcinosis . I would suggest you: - reduced calcium diet(avoid milk products, cheese and etc.); - continue pamidronate,it is inhibitor of bone resorption; - consume food enriched with Potassium, because it is Calcium antagonist(apricot, raisins,banana,potato and etc.) If you do not have any clarifications, you can close the discussion and rate the answer. Wish your daughter speedy recovery and good health!