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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Trimethylaminuria, Friends Hold Noses, Keep Distance, Turn On Fans, Open Windows

Please help me to get tested for TMAU , which i believe is recking my life. I work in an office but find it had to make friends as everyone avoids me. When i talk to them they hold their noses or keep a distance. When am at my desk the have fans on and windows wide open to get freah air, ( common complain is its very hot here) even in winter.
Mon, 25 Nov 2013
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Radiologist 's  Response
Hi,
Thanks for writing in to us.

Trimethylaminuria is a disorder in which the volatile, fish-smelling compound, trimethylamine (TMA) accumulates and is excreted in the urine, but is also found in the sweat and breath of these patients. Because many patients have associated body odours or halitosis, trimethylaminuria sufferers can meet serious difficulties in a social context, leading to other problems such as isolation and depression.

To date there has been no systematic appraisal of suggested treatments in this condition, but it seems clear that the various options have not been universally successful, particularly in severely affected individuals. At the very least, patients may benefit from being warned that the symptom may be exacerbated by febrile infections and during the perimenstrual period.

Use of deodorants with anti perspirants and having good diet can helps. Use anti microbial powder on your feet.

Hope this helps
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Trimethylaminuria, Friends Hold Noses, Keep Distance, Turn On Fans, Open Windows

Hi, Thanks for writing in to us. Trimethylaminuria is a disorder in which the volatile, fish-smelling compound, trimethylamine (TMA) accumulates and is excreted in the urine, but is also found in the sweat and breath of these patients. Because many patients have associated body odours or halitosis, trimethylaminuria sufferers can meet serious difficulties in a social context, leading to other problems such as isolation and depression. To date there has been no systematic appraisal of suggested treatments in this condition, but it seems clear that the various options have not been universally successful, particularly in severely affected individuals. At the very least, patients may benefit from being warned that the symptom may be exacerbated by febrile infections and during the perimenstrual period. Use of deodorants with anti perspirants and having good diet can helps. Use anti microbial powder on your feet. Hope this helps