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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Tot Suffered With Episode Of Convulsion In Sleep, Abnormal Eeg Test,prescribed Epilex. What Are Its Side Effects?

Sir, My son is 1 yeas and 8 months old. Recently while he was a sleep he encountered and episode of convulsion. The doctor advised to undergo eeg test which showed some abnormality. The doctor has not prescribed epilex syrup 1.5 ml thrice a day. I would like to know if its safe to give the syrup thrice a day and what would be its side effect. Kindly reply.
Fri, 19 Oct 2012
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Pediatrician, Cardiology,  's  Response
Hello
The EEG test is showing abnormality this suggest seizure disorder. Epilex contains valproic acid that is used as a first line drug in management of most of the seizures. In infants chances of liver function derangement is more common particularly in high doses. Dose of valproate is 10-40 mg/kg/day. You are giving 1.5 ml 8 hrly that means 180 mg daily( about 10-15 mg/kg/day). Common side effects may be nausea, vomiting due to liver involvement. So you are giving medicine in adequate doses and if you notice vomiting then consult your doc to rule out the cause of vomiting as a side effect of valproate.
With regards
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Tot Suffered With Episode Of Convulsion In Sleep, Abnormal Eeg Test,prescribed Epilex. What Are Its Side Effects?

Hello The EEG test is showing abnormality this suggest seizure disorder. Epilex contains valproic acid that is used as a first line drug in management of most of the seizures. In infants chances of liver function derangement is more common particularly in high doses. Dose of valproate is 10-40 mg/kg/day. You are giving 1.5 ml 8 hrly that means 180 mg daily( about 10-15 mg/kg/day). Common side effects may be nausea, vomiting due to liver involvement. So you are giving medicine in adequate doses and if you notice vomiting then consult your doc to rule out the cause of vomiting as a side effect of valproate. With regards