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Tests showed elevated SGOT, SGPT, uric acid, c-reactive protein, serum homocycteine. Analysis?

recently got my yearly comprehensive pathological & radiological tests done. Major standout results are SGOT 310, SGPT 62, Uric acid 8, cardio c-reactive protien, serum 6homocycteine, quantitative 17.01, lipoprotien (a) 36.1 I am indian male, 44 years, weight 100 kg what should I understand from these readings and what should be way forward?
Asked On : Tue, 9 Oct 2012
Answers:  1 Views:  265
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Pathologist and Microbiologist 's  Response
Hello and thank you for posting your query on HCM

I get the following information from your report:

SGOT levels are markedly raised

SGPT levels are raised

SGOT and SGPT are liver enzymes which are elevated in liver disease ie a disease causing damage to liver cells.

Since, the increase in SGOT is higher than that of SGPT, it indicates an acute liver injury most commonly alcohol induced liver injury.

In case you are consuming alcohol you will have to stop alcohol intake to get back your liver enzymes to normal level.

Your uric acid levels are also on higher side. Normally, it should be below 6mg/dl.

You should increase your water intake and reduce your red meat consumption in case you are taking lot of red meat. Besides reduce your protein intake for example reduce your intake of beans, pulses and of course alcochol.

After a week or so get your uric acid levels repeated. If it still remains high, consult your physician.

Your lipoprotein (a) level is high. Infact, it is in the group of high risk for cardiovascular diseases and cerebrovascular diseases. To put it simple you are at increased risk of heart attack ans stroke. Ideally, its level should be below 14mg/dl.

You have not mentioned the level of C-Reactive protein and homocysteine. These two are again markers of cardiovascular risk.

Last but not the least, your body weight is very high. However, I can only comment on it after knowing your height.

I can make things simple for by giving you a calculation which you can do yourself:

Body mass index (BMI)=Body weight in kg/ (Height in meters)²

If the value of BMI is between 19 and 24.9, your body weight is fine

If between 25 and 29.9 you are overweight

If above 30 you are obese

In any case, you need to visit your physician and get prescription to correct your lipoprotein (a) levels which is quite high.

Thanks and take care

Dr Shailja P Wahal
Answered: Tue, 9 Oct 2012
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