hi i had gone through your query and understand your concerns. i would come up with the possibility of RHEUMATOID ARTHRITIS may be the cause for his sufferings. -it is an autoimmune disease often run in families. -blood test for positive RA factor ( may be negative also ),increased CRP,ASO tritre,ESR may confirm the diagnosis. treatment option; i would suggest you taking Homeopathic medicines gives safe and permanent cure for his arthritic complaints consult your local homeopathic physician for correct diagnosis of the case and remedy to fit his complaints I hope this is helpful for you, thank you