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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Convulsions And Fever During Pregnancy

HIE i would like to inquire whats the best course of management for the below case. i have a lady who is 18years old , grav 3 para 2, at 24 weks gestation , she has fevers and has been convulsing hourly for the past week. she has history of Eclampsia in the previous pregnancy and lost her baby , miscarriage . antenatal visits Examination findings . GCS is 14/15 but no neck stiffness, she has normal Bps , the chest exam is unremarkable , the fundal height is 24 weeks , the Fetal beat is not heard ,no pedal oedema . the urine protein is negative, she got tested for malaria it is negative , then she had a lumber puncture , the csf analysis are still on going . her treatment course : phenorbarb, Diazepam , initial course of Quinine.
Tue, 26 Apr 2016
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General & Family Physician 's  Response
Hello dear
Understand your concern.
Fetal abnormality depend upon the seizure frequency and Level of the anti seizure drugs.
You should consult the best obstetricians and start the treatment of seizure.
90% delivery may be uncomplicated if done under the supervision of obstetricians, anesthetics and paediatricians.
First aim is to stop the seizure with first aid therapy and intravenous diazepam and then maintenance by phenytoin .
Injection/tablet paracetamol based on severity
Better to keep on mono therapy, As most of the the anti epileptic drugs are folate antagonist, they can cause congenital defects in the fetus.

At he time of labor there may be chance of fetus and mother distress, so labor should be closely supervised.
Vitamin K and folate should be given.

Hope this may help you
Best regards
Dr. sagar
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Suggest Treatment For Convulsions And Fever During Pregnancy

Hello dear Understand your concern. Fetal abnormality depend upon the seizure frequency and Level of the anti seizure drugs. You should consult the best obstetricians and start the treatment of seizure. 90% delivery may be uncomplicated if done under the supervision of obstetricians, anesthetics and paediatricians. First aim is to stop the seizure with first aid therapy and intravenous diazepam and then maintenance by phenytoin . Injection/tablet paracetamol based on severity Better to keep on mono therapy, As most of the the anti epileptic drugs are folate antagonist, they can cause congenital defects in the fetus. At he time of labor there may be chance of fetus and mother distress, so labor should be closely supervised. Vitamin K and folate should be given. Hope this may help you Best regards Dr. sagar