I have Ehler-Danlos (hybermobile) type and now have an extremely high CRP rat 34.4 (I believe anything over 7 is a concern). I've had 4 shoulder replacements. My orthopedic surgeon aspirated some fluid from the joint/prosthesis and has ruled out an infection there. Now my familiy doctor doesn't seem concerned at all with a 34.4 CRP reading but I am! I am 53 years old and have a lot of other symptoms as well, but my main concern right now is that my extremely high CRP may indicate something that should be treated right away - like cancer or lupus. There have been no tests ordered and I feel very confused about how much I should push my doctor to investigate this. By the way, my CRP has been elevated from a shoulder infection prior -- then it was only at 12 -- now at 34.4 that seems very frightening to me. My high sensitivity CRP test put me in the "average" range for heart disease. Do you have any suggestions for me?