Hi there ~ I am glad to hear of your concerns and thank you for asking your question on this online forum. While pioz or pioglitazone is an effective medication to control your diabetes and you have been having good control over your blood sugars, it might be that you are having problems with long term control. I am assuming this as your doctor, who hopefully is an internal medicine doctor specializing in diabetology, has recently changed your medication. I advise you to find out why this medication your changed by calling your doctor if you are not doing well with the medication change. I hope this helps. Take care and have a lovely day!