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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Chronic Granulomatous Lymphadenitis. Taking Medication. Is It Necessary To Take Pyrazinamide?

hi. i am 23 y.o suffering from chronic granulomatous lymphadenitis that is from biopsy of my lymph nodes on right neck. my doctor gave me ibjection streptomycin for 1 month plus rifampicin and isoniazid and vit b4 and omeprazole once a day then reasses me after that 1 month. my question is, do i need to take pyrazinamide? because it's not included in my medication and i told my doctor but he keeps on telling that there's no need for that and injection streptomycin is painful can i have alternative for that?i have been taking those medications for 7 days now. please i need your opinion.
Sat, 20 Jul 2013
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Pediatrician,  's  Response
Hi Dear
Welcome to the Health care Magic.

Dear friend, Anti Tubercular drugs should not be lees than four in initial phase and many times five also. Rifampicin and Isonex only will not be sufficient in this phase.

My opinion is, Pyrazinamide and combutol should also be added.

Atleast two months of PZA and Combu are necessary in order to avoid developing resistance cases and MDR TB.

Monitoring of Liver Function and Kidney function are a must during ATT.

For Tubercular Lymphadenopathy completion of total 18 months course is crucial.

Hope your query is answered and is useful to you.

Thanks
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Suffering From Chronic Granulomatous Lymphadenitis. Taking Medication. Is It Necessary To Take Pyrazinamide?

Hi Dear Welcome to the Health care Magic. Dear friend, Anti Tubercular drugs should not be lees than four in initial phase and many times five also. Rifampicin and Isonex only will not be sufficient in this phase. My opinion is, Pyrazinamide and combutol should also be added. Atleast two months of PZA and Combu are necessary in order to avoid developing resistance cases and MDR TB. Monitoring of Liver Function and Kidney function are a must during ATT. For Tubercular Lymphadenopathy completion of total 18 months course is crucial. Hope your query is answered and is useful to you. Thanks