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Although uncommon tamoxifen
can cause skin rash
and blisters. You have to stop the medication and usually it subside in a week or 2.
If the problem is severe you need to visit a dermatologist
If the skin reation is mild you can usually restart tamoxifen without any side effect.However if the problem is severe, you can discuss with your doctor regarding shifting from tamoxifen to aromitase inhibitors like Letrozole