thank you for your query and welcome to hcm community.
i am not sure what is causing the hand, feet and lip swelling
. Any family history of this problem ? Any colicky abdominal pain
? Any breathing difficulty ? Is it episodic and self limiting over several days & not responding to Antihistamine, Steroid
Assuming this edema is non-pitting and excluding the heart, liver, kidney and thyroid
causes, the thing that comes up in my mind is "Hereditary Angioedema" though all the clinical features dont match with it.
The cutaneous swelling is usually full, tight and non-itchy & dont respond to Antihistamines/Steroid. It can be aggravated by medication like ACE inhibitor
I would suggest you lab investigations C1 inhibitor level and C4 level just for the interest.
Hope, this helps. If you do the investigations then don't forget to inform me the result as i have curiosity of this rare genetic disorder.