hi i had gone through your query and understand your concerns. i would come up with the possibility ALLERGIC URTICARIA is the cause for your sufferings. -pain killers is the triggering factor in your case. Other conditions that can make allergic urticaria worsen are: -stress -extreme changes in weather (extreme heat and cold) -autoimmune diseases, such as thyroid disease or lupus Treatment As much as they may itch, avoid scratching your hives. This makes them spread further and it may break the skin’s surface, which makes you susceptible to skin infections. medicines I would suggest you taking Homeopathic medicines gives safe and permanent cure for your complaints consult your local homeopathic physician for correct diagnosis of the case and remedy to fit your complaints I hope this is helpful for you, thank you