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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Nerve Pain. Taking Medications, Swelling In Feet, Lower Legs. Side Effects?

I am on several different medications for severe nerve pain in my arm... vicodin, gabapentin, elavil, flexeril, and tramadol. I just finished a round of antibiotics and prednizone as well. I have horrible swelling in my feet, ankles and low legs, as well as tightness and pain about my upper belly. I am wondering if anyone can tell me if one or more of these medications could be causing this severe reaction with swelling and tightness?

Mon, 23 Sep 2013
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General & Family Physician 's  Response
Hello,
Thanks for the query to H.C.M. Forum.
As you mentioned that there is huge swelling over dependent parts such as legs, feet ankles .
However the drugs , mentioned above as vicodin, gabapentine , tramdol usually don't develop any swelling .
Antibiotics name , you haven't mentioned so can't say.
The prednisolone is a corticosteroid and this causes fluid retention in the body due to interfering in kidney function tests .
The main cause of swelling is prednisolone.
If you have taken this drug for long time then it may have causes depletion of calcium in bones, so consider this point also.
Now consult your treating doctor and get his opinion regarding this situation.
Good luck.
Dr. HET
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Nerve Pain. Taking Medications, Swelling In Feet, Lower Legs. Side Effects?

Hello, Thanks for the query to H.C.M. Forum. As you mentioned that there is huge swelling over dependent parts such as legs, feet ankles . However the drugs , mentioned above as vicodin, gabapentine , tramdol usually don t develop any swelling . Antibiotics name , you haven t mentioned so can t say. The prednisolone is a corticosteroid and this causes fluid retention in the body due to interfering in kidney function tests . The main cause of swelling is prednisolone. If you have taken this drug for long time then it may have causes depletion of calcium in bones, so consider this point also. Now consult your treating doctor and get his opinion regarding this situation. Good luck. Dr. HET