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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is There Any Link Between Cushings And Parkinson Disease?

My sister was small for her age and as she grew her hands and feet were disproporiately large. She was not overweight at first but became heavier as she was near puberty and except for a about a year continued to be heavy and was very strong. At age of about 50 she was diagnosed with Parkinson s and can no longer control the shaking. She is about 68 now. Is there a link between Cushings and Parkinsons? My granddaughter is now 13 and many for the same things are starting: very large hands and feet, her anger level in high as was my sister s, many other similarities are there. If such similarities exist is she also liable for Parkinson s?
Fri, 1 Jul 2016
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Neurologist 's  Response
I read your question carefully and I understand your concern.

Regarding the concern of a connection between Cushing and Parkinson's disease the answer is no, there is no known relation between the two conditions, the presence of both in your sister is a coincidence. She has developped Parkinson's at a pretty young age (usually after 65) and in these young onset cases there is thought to be a genetic predisposition, so the predisposition may be higher than in the common population.

As for the remaining issues, the larger hands and feet, anger issues, even if not related to Parkinson's she should see a doctor for the possibility of a pituitary adenoma.

I hope to have been of help.
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Is There Any Link Between Cushings And Parkinson Disease?

I read your question carefully and I understand your concern. Regarding the concern of a connection between Cushing and Parkinson s disease the answer is no, there is no known relation between the two conditions, the presence of both in your sister is a coincidence. She has developped Parkinson s at a pretty young age (usually after 65) and in these young onset cases there is thought to be a genetic predisposition, so the predisposition may be higher than in the common population. As for the remaining issues, the larger hands and feet, anger issues, even if not related to Parkinson s she should see a doctor for the possibility of a pituitary adenoma. I hope to have been of help.