Hi, Sifrol is a dopamine agonist used to treat Parkinson s disease symptoms such as tremors, stiffness, and problems with movement. It works by activating dopamine receptors in the brain. Sifrol is usually taken three times a day and may take several weeks to become effective. It can cause side effects such as dizziness, nausea, headache, and fatigue. Benzhexol is an anticholinergic medication that can help to reduce the tremors and muscle stiffness that are associated with Parkinson s disease. This medicine blocks the neurotransmitter s work called acetylcholine. Benzhexol is usually taken two to three times a day and can cause side effects such as dry mouth, constipation, and blurred vision. It is important to discuss any medication changes with your doctor before making any changes, as they can provide personalized advice based on your individual health history and current medications. They may also want to monitor your symptoms and adjust your dosage or medication regimen as needed. If you require a personalized response, kindly use the Ask A Doctor service and post a follow-up. Take care. Hope I have answered your question. Regards, Dr. Priyanka, General & Family Physician