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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is There A Clear Difference Between Histoplasmosis And Miliary TB?

Is there a clear difference between Histoplasmosis and Miliary TB. My tests so far indicate that at sometime I was exposed to Histo. But after lung wedge biopsy everything keeps on coming up negative ( but show I have the granulomas all over both my lungs). Plum. Dr. thinks we should try Itraconazole, Infectious Diseases is not sure and leaning towards TB.
Wed, 8 Jun 2016
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General Surgeon,  's  Response

Hi Dear !! Thanks for your query to HCM .
Read and reviewed your query and health concerns.
IN the given situation of Yours,You seem to suffer from-Histoplasmosis-which has micronodular lung pattern,and can mimick Miliary TB.
But immunocompromised body state in HIV patients,both could be present simultaneoulsy.Antigen testing in urine and serum is more sensitive (80%) in diagnosis of Histoplasmosis.
Other causes-like Sarcoidosis/blastomycosis need to be ruled out with Chest Physician Consults and CT chest and flexible bronchoscopy.
This plan would reduce your dilemma from histoplasmosis and Miliary TB.

Hope this would help you to plan further of this complex illness of yours.
If need be, update any health issue 24 x 7 by a direct question tod ME, at following HCM link-

Dear, if satisfied,Don't forget to close this query with YOUR pleasing feedback comments to rate this reply and service, to boost the morale of incoming Emergency patients like YOU, at HCM services.


If you want to update more details and ask more update queries ,
You are most Welcome herewith !!

Good Day!!

Wishing Good Healthy Life in time to come!!

Dr.Savaskar M.N.
Senior Surgical Specialist
M.S.Genl-CVTS
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Is There A Clear Difference Between Histoplasmosis And Miliary TB?

Hi Dear !! Thanks for your query to HCM . Read and reviewed your query and health concerns. IN the given situation of Yours,You seem to suffer from-Histoplasmosis-which has micronodular lung pattern,and can mimick Miliary TB. But immunocompromised body state in HIV patients,both could be present simultaneoulsy.Antigen testing in urine and serum is more sensitive (80%) in diagnosis of Histoplasmosis. Other causes-like Sarcoidosis/blastomycosis need to be ruled out with Chest Physician Consults and CT chest and flexible bronchoscopy. This plan would reduce your dilemma from histoplasmosis and Miliary TB. Hope this would help you to plan further of this complex illness of yours. If need be, update any health issue 24 x 7 by a direct question tod ME, at following HCM link- Dear, if satisfied,Don t forget to close this query with YOUR pleasing feedback comments to rate this reply and service, to boost the morale of incoming Emergency patients like YOU, at HCM services. If you want to update more details and ask more update queries , You are most Welcome herewith !! Good Day!! Wishing Good Healthy Life in time to come!! Dr.Savaskar M.N. Senior Surgical Specialist M.S.Genl-CVTS