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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Induction Therapy Necessary For Lyrics Tumors In Skull And Neck?

I have four very small lytics tumors in my skull and neck. My plasna cells from bone marrow biopsy is 15 B1. I am negative for Kappa and Lambda light chains. I have no symptoms at present or other labs that are abnormal. I have had IGA gamopathy for 30 years ranging from 1000 to 1600 with no other symptoms. My oncologist want to start induction therapy of Velcade T30 injection under the skin and 40mg of decadrom once a week. Since my case is mild, am I ready for induction thrapy?
Sat, 3 Sep 2016
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Neurologist, Surgical 's  Response
Hi,
as you are having 4 small lytic tumors and IGA gamopathy for 30 yrs with no other symptoms.you are not candidate for induction therapy.
Distinguishing between MM and MGUS is critical because patients with MGUS are conservatively treated and do not need chemotherapy.
In contrast, MM is a uniformly lethal disease that varies from a disease that does not need therapy at first to an advanced or aggressive stage that requires therapy . Thanks
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Is Induction Therapy Necessary For Lyrics Tumors In Skull And Neck?

Hi, as you are having 4 small lytic tumors and IGA gamopathy for 30 yrs with no other symptoms.you are not candidate for induction therapy. Distinguishing between MM and MGUS is critical because patients with MGUS are conservatively treated and do not need chemotherapy. In contrast, MM is a uniformly lethal disease that varies from a disease that does not need therapy at first to an advanced or aggressive stage that requires therapy . Thanks