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465 U/L is quite high.It is not possible to interpret the meaning of an abnormally high CA 125 without additional information about the particular patient being evaluated. The reason is that blood levels of this protein can be increased in many different benign and malignant conditions. In the patient who is being evaluated for a pelvic mass, a CA 125 level greater than 65 is associated with malignancy in approximately 90% of cases. However, without a demonstrable mass, the association is much weaker. If it is due to ovarian cancer
treatment depends upon stage of cancer. Treating gynecologist/oncologist
will be in better situation to comment on prognosis( curability ). Take care.