The three clinical variants of the disease consist of a primary acute disorder of young persons, a primary chronic disorder of older persons and a secondary disorder associated with benign or malignant disease. The primary disorder of young person consists of focal skin lesion with slight progression and spontaneously resolves between 2 months and 2 years. Primary chronic alopecia mucinosa of older persons affects people older than 40 years. Lesions have a widespread distribution and they may persist or recur indefinitely. The secondary alopecia mucinosa may be associated with either benign disease or malignant disease. Benign diseases include the inflammatory conditions like lupus erythematosus, lichen simplex chronicus, leprosy, alopecia areata and angiolymphoid hyperplasia.Secondary alopecia mucinosa is also associated with malignant disease, including mycosis fungoides, Kaposi's sarcoma and Hodgkin disease.