Dear! Thanks for writing to HCM! This is Dr.Suleman Resident in Cardiology in Cardiac Rehabilitation Centre! By Your query I came to know you are looking for some novel treatment for Cardiac Syndromes X. You seems to have pretty good knowledge about your disease so let me give you an overview of new therapies. EECP (Enhance External Counter Pulsation) is a new treatment strategy of angina for patients like you. In our centre it cost 1000 US dollars. and there are 36 session each one consisting of 1 hour. So you have to visit the centre 36 days. This therapy helps you by making new vessels that supply blood to your heart and improve its contractility. Its even alternative to exercise. Research showed excellent reduction in angina. Another therapy is Spinal Cord stimulation. it helps 50% patients who are resistant to all treatment you mentioned in your query. Apart from above treatment modalities psychotherapy, diet modification and regular exercise along with smoking cessation can reduce your symptoms. Assess your self and see which change you made in your life which is resulting in poor control of the pain. Stay Healthy and Get Well Soon