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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Does Morphology Affect IUI?

My husband and I are coming up on 2 years of trying to conceive. We recently finished all the testing and found my husband's morphology is at 2 percent. We are waiting on another analysis to confirm the results. Our doctor recommended IVF (which we cannot afford) as our only option stating our odds of conceiving through IUI was at 6%. We were both crushed and went online to research but we have found very conflicting information. We have found studies stating morphology (the only abnormal result) can't predict the outcome of an IUI where other studies stated a 2% kuger score said there was a slim to none chance of IUI working. IUI right now is our only option. What is the real story about morphology?
Mon, 19 Oct 2015
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Urologist,  's  Response
What you have read is partially true. Sperm morphology as measured by the so called Krugerberg Strict criteria does correlate with pregnancy outcomes, but I would also like to know the sperm count. If the sperm count is very high, a low morphology will not be very detrimental, as you should understand that even among men who have conceived normally, the sperm morphology as measured by the strict criteria will be quite often only 5-8%. We have seen people with 1% morphology conceiving and therefore this is not the end of the world. See if you can start making lifestyle changes and start yourselves on nutraceuticals to help me improve morphology, especially if you cannot afford a test tube baby at this stage.
All the best wishes.
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How Does Morphology Affect IUI?

What you have read is partially true. Sperm morphology as measured by the so called Krugerberg Strict criteria does correlate with pregnancy outcomes, but I would also like to know the sperm count. If the sperm count is very high, a low morphology will not be very detrimental, as you should understand that even among men who have conceived normally, the sperm morphology as measured by the strict criteria will be quite often only 5-8%. We have seen people with 1% morphology conceiving and therefore this is not the end of the world. See if you can start making lifestyle changes and start yourselves on nutraceuticals to help me improve morphology, especially if you cannot afford a test tube baby at this stage. All the best wishes.